TY - JOUR
T1 - Postpartum hypercalcemia in a patient with previous thyroid carcinoma
T2 - a report of 2 cases
AU - Yasumatsu, Ryuji
AU - Nakashima, Torahiko
AU - Kuratomi, Yuichiro
AU - Komiyama, Sohtaro
PY - 2002/8
Y1 - 2002/8
N2 - We report postpartum hypercalcemia in 2 patients with previous thyroid carcinoma who had undergone total thyroidectomy and total parathyroidectomy and required vitamin D and calcium therapy to control hypoparathyroidism. Postpartum, they required less vitamin D and calcium for satisfactory control. While lactating, they maintained normal serum calcium without supplementary vitamin D or calcium. Transient remission of hypoparathyroidism symptoms has been observed during lactation. Some studies have shown that parathyroid-related protein (PTHrP) is produced by breast tissue, having an endocrine-like effect. We discuss the mechanism of postpartum hypercalcemia.
AB - We report postpartum hypercalcemia in 2 patients with previous thyroid carcinoma who had undergone total thyroidectomy and total parathyroidectomy and required vitamin D and calcium therapy to control hypoparathyroidism. Postpartum, they required less vitamin D and calcium for satisfactory control. While lactating, they maintained normal serum calcium without supplementary vitamin D or calcium. Transient remission of hypoparathyroidism symptoms has been observed during lactation. Some studies have shown that parathyroid-related protein (PTHrP) is produced by breast tissue, having an endocrine-like effect. We discuss the mechanism of postpartum hypercalcemia.
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U2 - 10.3950/jibiinkoka.105.897
DO - 10.3950/jibiinkoka.105.897
M3 - Article
C2 - 12235885
AN - SCOPUS:0036690954
SN - 0030-6622
VL - 105
SP - 897
EP - 900
JO - Nippon Jibiinkoka Gakkai kaiho
JF - Nippon Jibiinkoka Gakkai kaiho
IS - 8
ER -