Polysaccharide-polynucleotide complexes (IV): Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines

Kazuya Koumoto; Taro Kimura; Kazuo Sakurai; Seiji Shinkai

doi:10.1006/bioo.2001.1202

Polysaccharide-polynucleotide complexes (IV): Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines

Kazuya Koumoto
, Taro Kimura
, Kazuo Sakurai
, Seiji Shinkai

Research output: Contribution to journal › Editorial › peer-review

11 Citations (Scopus)

Abstract

Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.

Original language	English
Pages (from-to)	178-185
Number of pages	8
Journal	Bioorganic Chemistry
Volume	29
Issue number	3
DOIs	https://doi.org/10.1006/bioo.2001.1202
Publication status	Published - Jun 2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Drug Discovery
Organic Chemistry

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10.1006/bioo.2001.1202

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title = "Polysaccharide-polynucleotide complexes (IV): Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines",

abstract = "Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80\% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.",

author = "Kazuya Koumoto and Taro Kimura and Kazuo Sakurai and Seiji Shinkai",

year = "2001",

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journal = "Bioorganic Chemistry",

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T1 - Polysaccharide-polynucleotide complexes (IV)

T2 - Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines

AU - Koumoto, Kazuya

AU - Kimura, Taro

AU - Sakurai, Kazuo

AU - Shinkai, Seiji

PY - 2001/6

Y1 - 2001/6

N2 - Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.

AB - Polymer complexes formed by schizophyllan and poly(C) showed a unique antihydrolysis effect when poly(C) was subjected to hydrolysis under basic conditions. The complexation reduced the hydrolysis rate to 80% of the control (i.e., poly(C) itself). However, when we added oligoamines with the intention of catalyzing the hydrolysis, the oligoamines induced dissociation of the complex instead of acceleration of the hydrolysis.

UR - https://www.scopus.com/pages/publications/0035574756

UR - https://www.scopus.com/pages/publications/0035574756#tab=citedBy

U2 - 10.1006/bioo.2001.1202

DO - 10.1006/bioo.2001.1202

M3 - Editorial

C2 - 11437393

AN - SCOPUS:0035574756

SN - 0045-2068

VL - 29

SP - 178

EP - 185

JO - Bioorganic Chemistry

JF - Bioorganic Chemistry

IS - 3

ER -

Polysaccharide-polynucleotide complexes (IV): Antihydrolysis effect of the schizophyllan/poly(C) complex and the complex dissociation induced by amines

Abstract

All Science Journal Classification (ASJC) codes

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