PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser

Takahito Kawano; Yasuro Niidome; Takeshi Mori; Yoshiki Katayama; Takuro Niidome

doi:10.1021/bc800480k

PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser

Takahito Kawano, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome

Center for Advanced Medical Open Innovation

Research output: Contribution to journal › Article › peer-review

229 Citations (Scopus)

Abstract

Gold nanorods can be used as photothermal converters, permitting near-infrared (NIR) light to be transmitted deep into tissues without causing damage. We prepared hybrid nanorods with a core-shell structure, i.e., a single gold nanorod encapsulated in a poly (N-isopropylacrylamide) nanogel. Hybrid nanorods demonstrated remote, reversible, pulsatile phase transition and in vivo action after irradiation using a NIR laser.

Original language	English
Pages (from-to)	209-212
Number of pages	4
Journal	Bioconjugate Chemistry
Volume	20
Issue number	2
DOIs	https://doi.org/10.1021/bc800480k
Publication status	Published - Feb 2009

All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Biomedical Engineering
Pharmacology
Pharmaceutical Science
Organic Chemistry

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10.1021/bc800480k

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abstract = "Gold nanorods can be used as photothermal converters, permitting near-infrared (NIR) light to be transmitted deep into tissues without causing damage. We prepared hybrid nanorods with a core-shell structure, i.e., a single gold nanorod encapsulated in a poly (N-isopropylacrylamide) nanogel. Hybrid nanorods demonstrated remote, reversible, pulsatile phase transition and in vivo action after irradiation using a NIR laser.",

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AU - Katayama, Yoshiki

AU - Niidome, Takuro

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PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser

Abstract

All Science Journal Classification (ASJC) codes

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