Abstract
Two infants with Diamond-Blackfan anemia (DBA) developed Pneumocystis carinii pneumonia during corticosteroid (CS) therapy. Both patients showed the typical prodrome of tachypnea and fever, and the chest X-ray findings of interstitial infiltration, along with high serum levels of β-D-glucan and undetectable levels of endotoxin. The PCR study of bronchoalveolar lavage fluid was positive for P. carinii DNA in a 4-month-old infant, although it was not available in the previous case of a 2-month-old infant. No other causative agents were defined. They had no predisposing immunodeficiency diseases. Prophylaxis against P. carinii infection must be considered for young infants with DBA during the first CS therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 7-11 |
| Number of pages | 5 |
| Journal | International Journal of Pediatric Hematology/Oncology |
| Volume | 7 |
| Issue number | 1 |
| Publication status | Published - 2000 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Hematology
- Cancer Research
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