TY - JOUR
T1 - Pleomorphic adenoma originating from submandibular heterotopic salivary gland tissue
T2 - A case report and review of the literature
AU - Kubota, Yasutaka
AU - Nitta, Shuichi
AU - Takenoshita, Yasuharu
AU - Shimizu, Mayumi
AU - Shirasuna, Kanemitsu
PY - 2005/5
Y1 - 2005/5
N2 - We reported a case of pleomorphic adenoma originating from the submandibular heterotopic salivary gland tissue (HGST) of a 61-year-old man. Histologically, no lymphoid tissue was detected in the tumor. Immunohistochemical examination revealed that the luminal tumor cells of tubuloductal structures were positive for anti-α-amylase antibody. The outer tumor cells of tubuloductal structures and neoplastic myoepithelial cells were stained with K8.12, anti-vimentin antibody, and anti-S-100 protein antibody. No tumor cells reacted with anti-α-smooth muscle actin antibody. These suggest that the tumor cells may be derived from the ductal cells of the extranodal HSGT. No recurrence of the tumor was detected for seven years.
AB - We reported a case of pleomorphic adenoma originating from the submandibular heterotopic salivary gland tissue (HGST) of a 61-year-old man. Histologically, no lymphoid tissue was detected in the tumor. Immunohistochemical examination revealed that the luminal tumor cells of tubuloductal structures were positive for anti-α-amylase antibody. The outer tumor cells of tubuloductal structures and neoplastic myoepithelial cells were stained with K8.12, anti-vimentin antibody, and anti-S-100 protein antibody. No tumor cells reacted with anti-α-smooth muscle actin antibody. These suggest that the tumor cells may be derived from the ductal cells of the extranodal HSGT. No recurrence of the tumor was detected for seven years.
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U2 - 10.1016/j.ooe.2005.02.002
DO - 10.1016/j.ooe.2005.02.002
M3 - Article
AN - SCOPUS:19444370324
SN - 1741-9409
VL - 41
SP - 93
EP - 96
JO - Oral Oncology Extra
JF - Oral Oncology Extra
IS - 5
ER -