Platelet adhesion on films of poly(vinylene carbonate) and its derivatives

Hisao Matsuno; Ryota Tsukamoto; Yu Kaneshiro; Satoru Yamada; Keiji Tanaka

doi:10.1246/cl.160373

Platelet adhesion on films of poly(vinylene carbonate) and its derivatives

Hisao Matsuno, Ryota Tsukamoto, Yu Kaneshiro, Satoru Yamada, Keiji Tanaka

Research output: Contribution to journal › Article › peer-review

Abstract

Poly(vinylene carbonate) (PVCA) and poly(β-hydroxyvinyl N-substituted carbamate)s (PHCs) were synthesized by radical polymerization and aminolysis reactions of PVCA, respectively. The relation between the surface aggregation states of these polymers and the blood platelet adhesion behaviors on them was examined. Results showed that the number and activation degree of platelets on the various PHC films were strongly correlated to their surface/interfacial free energies, while such was not the case for the PVCA film.

Original language	English
Pages (from-to)	913-915
Number of pages	3
Journal	Chemistry Letters
Volume	45
Issue number	8
DOIs	https://doi.org/10.1246/cl.160373
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.160373

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title = "Platelet adhesion on films of poly(vinylene carbonate) and its derivatives",

abstract = "Poly(vinylene carbonate) (PVCA) and poly(β-hydroxyvinyl N-substituted carbamate)s (PHCs) were synthesized by radical polymerization and aminolysis reactions of PVCA, respectively. The relation between the surface aggregation states of these polymers and the blood platelet adhesion behaviors on them was examined. Results showed that the number and activation degree of platelets on the various PHC films were strongly correlated to their surface/interfacial free energies, while such was not the case for the PVCA film.",

author = "Hisao Matsuno and Ryota Tsukamoto and Yu Kaneshiro and Satoru Yamada and Keiji Tanaka",

note = "Funding Information: This research was partially supported by the JSPS KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas {"}New Polymeric Materials Based on Element-Blocks{"} (No. 15H00758) program, Grant-in-Aids for Scientific Research (A) (No. 15H02183) and for Scientific Research (C) (No. 15K05633). We also appreciate the support from the JST SENTANKEISOKU (No. 13A0004). Publisher Copyright: {\textcopyright} 2016 The Chemical Society of Japan.",

year = "2016",

doi = "10.1246/cl.160373",

language = "English",

volume = "45",

pages = "913--915",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "The Chemical Society of Japan",

number = "8",

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TY - JOUR

T1 - Platelet adhesion on films of poly(vinylene carbonate) and its derivatives

AU - Matsuno, Hisao

AU - Tsukamoto, Ryota

AU - Kaneshiro, Yu

AU - Yamada, Satoru

AU - Tanaka, Keiji

N1 - Funding Information: This research was partially supported by the JSPS KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas "New Polymeric Materials Based on Element-Blocks" (No. 15H00758) program, Grant-in-Aids for Scientific Research (A) (No. 15H02183) and for Scientific Research (C) (No. 15K05633). We also appreciate the support from the JST SENTANKEISOKU (No. 13A0004). Publisher Copyright: © 2016 The Chemical Society of Japan.

PY - 2016

Y1 - 2016

N2 - Poly(vinylene carbonate) (PVCA) and poly(β-hydroxyvinyl N-substituted carbamate)s (PHCs) were synthesized by radical polymerization and aminolysis reactions of PVCA, respectively. The relation between the surface aggregation states of these polymers and the blood platelet adhesion behaviors on them was examined. Results showed that the number and activation degree of platelets on the various PHC films were strongly correlated to their surface/interfacial free energies, while such was not the case for the PVCA film.

AB - Poly(vinylene carbonate) (PVCA) and poly(β-hydroxyvinyl N-substituted carbamate)s (PHCs) were synthesized by radical polymerization and aminolysis reactions of PVCA, respectively. The relation between the surface aggregation states of these polymers and the blood platelet adhesion behaviors on them was examined. Results showed that the number and activation degree of platelets on the various PHC films were strongly correlated to their surface/interfacial free energies, while such was not the case for the PVCA film.

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DO - 10.1246/cl.160373

M3 - Article

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VL - 45

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EP - 915

JO - Chemistry Letters

JF - Chemistry Letters

IS - 8

ER -

Platelet adhesion on films of poly(vinylene carbonate) and its derivatives

Abstract

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