Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Nampoina Andriamisaina; Anne Claire Mitaine-Offer; Benoist Pruvot; Johanna Chluba; Tomofumi Miyamoto; Chiaki Tanaka; Marie Aleth Lacaille-Dubois

doi:10.1177/1934578x1801300406

Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Nampoina Andriamisaina, Anne Claire Mitaine-Offer, Benoist Pruvot, Johanna Chluba, Tomofumi Miyamoto, Chiaki Tanaka, Marie Aleth Lacaille-Dubois

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

One new triterpene glycoside 3-O-D-xylopyranosyl-(1→4)-[-D-glucopyranosyl-(1→3)]-D-xylopyranosyl-(1→4)-D-xylopyranosyl-(1→3)-L-rhamnopyranosyl-(1→2)-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including ¹H- and ¹³C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 M.

Original language	English
Pages (from-to)	403-406
Number of pages	4
Journal	Natural product communications
Volume	13
Issue number	4
DOIs	https://doi.org/10.1177/1934578x1801300406
Publication status	Published - Apr 2018

All Science Journal Classification (ASJC) codes

Pharmacology
Drug Discovery
Plant Science
Complementary and alternative medicine

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title = "Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)",

abstract = "One new triterpene glycoside 3-O-D-xylopyranosyl-(1→4)-[-D-glucopyranosyl-(1→3)]-D-xylopyranosyl-(1→4)-D-xylopyranosyl-(1→3)-L-rhamnopyranosyl-(1→2)-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including 1H- and 13C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 M.",

author = "Nampoina Andriamisaina and Mitaine-Offer, {Anne Claire} and Benoist Pruvot and Johanna Chluba and Tomofumi Miyamoto and Chiaki Tanaka and Lacaille-Dubois, {Marie Aleth}",

note = "Funding Information: Acknowledgments - The authors would like to thank Tatiana Lopez for fish care, and the Conseil R{\'e}gional de Bourgogne (PARI program) and the FEDER program for financial support. Publisher Copyright: {\textcopyright} 2018 Natural Product Incorporation. All rights reserved.",

year = "2018",

month = apr,

doi = "10.1177/1934578x1801300406",

language = "English",

volume = "13",

pages = "403--406",

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AU - Andriamisaina, Nampoina

AU - Mitaine-Offer, Anne Claire

AU - Pruvot, Benoist

AU - Chluba, Johanna

AU - Miyamoto, Tomofumi

AU - Tanaka, Chiaki

AU - Lacaille-Dubois, Marie Aleth

N1 - Funding Information: Acknowledgments - The authors would like to thank Tatiana Lopez for fish care, and the Conseil Régional de Bourgogne (PARI program) and the FEDER program for financial support. Publisher Copyright: © 2018 Natural Product Incorporation. All rights reserved.

PY - 2018/4

Y1 - 2018/4

N2 - One new triterpene glycoside 3-O-D-xylopyranosyl-(1→4)-[-D-glucopyranosyl-(1→3)]-D-xylopyranosyl-(1→4)-D-xylopyranosyl-(1→3)-L-rhamnopyranosyl-(1→2)-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including 1H- and 13C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 M.

AB - One new triterpene glycoside 3-O-D-xylopyranosyl-(1→4)-[-D-glucopyranosyl-(1→3)]-D-xylopyranosyl-(1→4)-D-xylopyranosyl-(1→3)-L-rhamnopyranosyl-(1→2)-L-arabinopyranosyloleanolic acid, was isolated from Weigela x “kosteriana variegata” (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including 1H- and 13C NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 M.

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Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Abstract

All Science Journal Classification (ASJC) codes

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