PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues

Yasuyuki Akiyama, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)


    Gold nanorods modified with polyethylene glycol (PEG) chains via Au-S bonds form aggregates, and their absorption spectra broaden in tumor tissues. In contrast, the gold nanorods modified here via the crosslinking of PEG chains on the silica shell on gold nanorods showed enhanced permeability and retention effects and retained the optical properties of the original gold nanorods in tumor tissues.

    Original languageEnglish
    Pages (from-to)2071-2080
    Number of pages10
    JournalJournal of Biomaterials Science, Polymer Edition
    Issue number18
    Publication statusPublished - Dec 1 2013

    All Science Journal Classification (ASJC) codes

    • Biophysics
    • Bioengineering
    • Biomaterials
    • Biomedical Engineering


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