Pd(en) as a sequence-selective molecular pinch for α-helical peptides

Itaru Hamachi, Noriyuki Kasagi, Shigeki Kiyonaka, Tsuyoshi Nagase, Yasuko Mito-Oka, Seiji Shinkai

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A palladium(II)(ethylenediamine) complex was found to selectively stabilize α-helix conformation of peptides having two histidine (His) residues at i and i + (3 or 4) positions, whereas the helix conformation of the other peptides having one or two His at different positions is destabilized.

Original languageEnglish
Pages (from-to)16-17
Number of pages2
JournalChemistry Letters
Issue number1
Publication statusPublished - 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry


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