TY - JOUR
T1 - Pathophysiology and treatment of hoarding disorder
AU - Nakao, Tomohiro
AU - Kanba, Shigenobu
N1 - Funding Information:
The authors would like to thank Dr Keitaro Murayama, Dr Satoshi Yamada, Dr Masumi Kuwano, Dr Keisuke Ikari, Dr Hirofumi Tomiyama, Dr Suguru Hasuzawa, and Dr Taro Mizobe for their research assistance. The authors also thank Ms Katherine Ono for providing helpful advice with language. This work was supported by a Grant-in-Aid for Scientific Research (C) (18K07603; 15K09834) from the Japanese Ministry of Education, Culture, Sports, Science, and Technology.
Publisher Copyright:
© 2019 The Authors. Psychiatry and Clinical Neurosciences © 2019 Japanese Society of Psychiatry and Neurology
PY - 2019/7
Y1 - 2019/7
N2 - Hoarding disorder (HD) is a newly listed disease in the new category of Obsessive–Compulsive and Related Disorders in the DSM-5. Patients with HD find it difficult to discard possessions regardless of their actual value and to organize those things. As a result, the possessions overflow the living space and hinder living functions. Though the hoarding symptom had been regarded as a subtype of obsessive–compulsive disorder (OCD) to date, recent studies have revealed many differences in clinical characteristics, including onset, course, degree of insight, and treatment responses, between hoarding and other subtypes. Moreover, several neuroimaging studies have found specific changes of brain structure and function in OCD patients with hoarding symptoms compared to patients with non-hoarding OCD. Meanwhile, strategies for treatment of HD have not been standardized. At present, psychological treatment using cognitive behavioral therapy techniques has a certain effect. In this review, we outline the pathophysiology and treatment of HD.
AB - Hoarding disorder (HD) is a newly listed disease in the new category of Obsessive–Compulsive and Related Disorders in the DSM-5. Patients with HD find it difficult to discard possessions regardless of their actual value and to organize those things. As a result, the possessions overflow the living space and hinder living functions. Though the hoarding symptom had been regarded as a subtype of obsessive–compulsive disorder (OCD) to date, recent studies have revealed many differences in clinical characteristics, including onset, course, degree of insight, and treatment responses, between hoarding and other subtypes. Moreover, several neuroimaging studies have found specific changes of brain structure and function in OCD patients with hoarding symptoms compared to patients with non-hoarding OCD. Meanwhile, strategies for treatment of HD have not been standardized. At present, psychological treatment using cognitive behavioral therapy techniques has a certain effect. In this review, we outline the pathophysiology and treatment of HD.
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U2 - 10.1111/pcn.12853
DO - 10.1111/pcn.12853
M3 - Review article
C2 - 31021515
AN - SCOPUS:85066142160
SN - 1323-1316
VL - 73
SP - 370
EP - 375
JO - Psychiatry and clinical neurosciences
JF - Psychiatry and clinical neurosciences
IS - 7
ER -
