TY - JOUR
T1 - Palladium-catalyzed addition reaction of thioesters to norbornenes
AU - Arisawa, Mieko
AU - Tanii, Saori
AU - Yamada, Tomoki
AU - Yamaguchi, Masahiko
N1 - Funding Information:
This work was supported by Platform for Drug Discovery, Informatics, and Structural Life Science from the Ministry of Education, Culture, Sports, Science and Technology, Japan . M.A. expresses her appreciation to the financial supports from the Grant-in-Aid for Scientific Research (No. 25109503 and 15H00911 ), and the research grant of Astellas Foundation for Research on Metabolic Disorders.
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/8/7
Y1 - 2015/8/7
N2 - Abstract A palladium complex derived from Pd2(dba)3 and tris(2,4,6-trimethoxyphenyl)phosphine catalyzes the addition reaction of thioesters to norbornenes, giving trans-2-acyl -3-organothionorbornanes. The trans-adducts are predominantly obtained with the acyl group at the endo-position and the organothio group at the exo-position. Aroyl and heteroaroyl thioesters as well as alkanoyl thioesters were reacted, including S-(4-tolyl) phenylthioglyoxylate and methyl 2-(4-tolylthio)-2-oxo-acetate.
AB - Abstract A palladium complex derived from Pd2(dba)3 and tris(2,4,6-trimethoxyphenyl)phosphine catalyzes the addition reaction of thioesters to norbornenes, giving trans-2-acyl -3-organothionorbornanes. The trans-adducts are predominantly obtained with the acyl group at the endo-position and the organothio group at the exo-position. Aroyl and heteroaroyl thioesters as well as alkanoyl thioesters were reacted, including S-(4-tolyl) phenylthioglyoxylate and methyl 2-(4-tolylthio)-2-oxo-acetate.
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U2 - 10.1016/j.tet.2015.05.042
DO - 10.1016/j.tet.2015.05.042
M3 - Article
AN - SCOPUS:84938739831
SN - 0040-4020
VL - 71
SP - 6449
EP - 6458
JO - Tetrahedron
JF - Tetrahedron
IS - 37
M1 - 26760
ER -