Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii

Mikita Suyama; Warren C. Lathe; Peer Bork

doi:10.1016/j.febslet.2005.08.051

Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii

Mikita Suyama, Warren C. Lathe, Peer Bork

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9% of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions.

Original language	English
Pages (from-to)	5281-5286
Number of pages	6
Journal	FEBS Letters
Volume	579
Issue number	24
DOIs	https://doi.org/10.1016/j.febslet.2005.08.051
Publication status	Published - Oct 10 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/j.febslet.2005.08.051

Cite this

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title = "Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii",

abstract = "We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9% of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions.",

author = "Mikita Suyama and Lathe, {Warren C.} and Peer Bork",

note = "Funding Information: We thank anonymous reviewers for valuable comments. This work was supported by EU Grant (LSHG-CT-2003-503265) to P.B. ",

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T1 - Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii

AU - Suyama, Mikita

AU - Lathe, Warren C.

AU - Bork, Peer

N1 - Funding Information: We thank anonymous reviewers for valuable comments. This work was supported by EU Grant (LSHG-CT-2003-503265) to P.B.

PY - 2005/10/10

Y1 - 2005/10/10

N2 - We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9% of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions.

AB - We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9% of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions.

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Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii

Abstract

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