Oxygen saturation imaging of human retinal vessels and measurement in eye disease patient for clinical application

D. Nakamura, N. Matsuoka, K. Tatsuguchi, M. Ogata, Y. Yoshinaga, H. Enaida, T. Okada, T. Ishibashi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)


We have proposed a new automatic visualization procedure based the ratio of optical densities (ODs) obtained at two different wavelength for the oxygen saturation imaging in human retinal vessels. This method utilized the morphological processing and the line convergence index filter to estimate the reflection image of outside vessels and extract the vessel structure from retinal image, respectively. In the experimental measurement, clear difference between retinal arteries and veins has been observed. In this study, the data processing technique of the line convergence index filter was applied to a color fundus image to investigate the ability of vessel extraction. In addition, four-wavelength imaging was proposed to evaluate oxygen saturation of the retinal capillary vessels and to decrease the influence of the melanin pigmentation.

Original languageEnglish
Title of host publicationOphthalmic Technologies XX
Publication statusPublished - 2010
EventOphthalmic Technologies XX - San Francisco, CA, United States
Duration: Jan 23 2010Jan 25 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherOphthalmic Technologies XX
Country/TerritoryUnited States
CitySan Francisco, CA

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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