Oxidative Synthesis of α-Nitroketones from α-Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents

Yujiro Hayashi; Emanuele Cocco; Hinata Odaira; Hiroaki Matoba; Naoki Mori

doi:10.1002/ejoc.202300964

Oxidative Synthesis of α-Nitroketones from α-Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents

Yujiro Hayashi, Emanuele Cocco, Hinata Odaira, Hiroaki Matoba, Naoki Mori

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We developed an oxidative synthetic method for α-nitroketones from α-substituted malononitriles and nitromethane under molecular oxygen. Only base and molecular oxygen are necessary without condensation reagents; this is an environmentally benign synthesis.

Original language	English
Article number	e202300964
Journal	European Journal of Organic Chemistry
Volume	27
Issue number	6
DOIs	https://doi.org/10.1002/ejoc.202300964
Publication status	Published - Feb 12 2024
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1002/ejoc.202300964

Cite this

@article{f38691282ce04b31987bd38ce09c0a20,

title = "Oxidative Synthesis of α-Nitroketones from α-Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents",

abstract = "We developed an oxidative synthetic method for α-nitroketones from α-substituted malononitriles and nitromethane under molecular oxygen. Only base and molecular oxygen are necessary without condensation reagents; this is an environmentally benign synthesis.",

keywords = "malononitriles, nitromethane, oxidation, oxygen, α-nitroketone",

author = "Yujiro Hayashi and Emanuele Cocco and Hinata Odaira and Hiroaki Matoba and Naoki Mori",

note = "Publisher Copyright: {\textcopyright} 2023 Wiley-VCH GmbH.",

year = "2024",

month = feb,

day = "12",

doi = "10.1002/ejoc.202300964",

language = "English",

volume = "27",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH Verlag",

number = "6",

}

TY - JOUR

T1 - Oxidative Synthesis of α-Nitroketones from α-Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents

AU - Hayashi, Yujiro

AU - Cocco, Emanuele

AU - Odaira, Hinata

AU - Matoba, Hiroaki

AU - Mori, Naoki

PY - 2024/2/12

Y1 - 2024/2/12

N2 - We developed an oxidative synthetic method for α-nitroketones from α-substituted malononitriles and nitromethane under molecular oxygen. Only base and molecular oxygen are necessary without condensation reagents; this is an environmentally benign synthesis.

AB - We developed an oxidative synthetic method for α-nitroketones from α-substituted malononitriles and nitromethane under molecular oxygen. Only base and molecular oxygen are necessary without condensation reagents; this is an environmentally benign synthesis.

KW - malononitriles

KW - nitromethane

KW - oxidation

KW - oxygen

KW - α-nitroketone

UR - http://www.scopus.com/inward/record.url?scp=85182498282&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85182498282&partnerID=8YFLogxK

U2 - 10.1002/ejoc.202300964

DO - 10.1002/ejoc.202300964

M3 - Article

AN - SCOPUS:85182498282

SN - 1434-193X

VL - 27

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 6

M1 - e202300964

ER -

Oxidative Synthesis of α-Nitroketones from α-Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this