Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii

Satoru Yokoyama; Tran Hai Bang; Kuniyoshi Shimizu; Ryuichiro Kondo

doi:10.1177/1934578x1200700913

Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii

Satoru Yokoyama, Tran Hai Bang, Kuniyoshi Shimizu, Ryuichiro Kondo

Sustainable Bioresources Science

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 μg/mL.

Original language	English
Pages (from-to)	1163-1164
Number of pages	2
Journal	Natural product communications
Volume	7
Issue number	9
DOIs	https://doi.org/10.1177/1934578x1200700913
Publication status	Published - Sept 2012

All Science Journal Classification (ASJC) codes

Pharmacology
Plant Science
Drug Discovery
Complementary and alternative medicine

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10.1177/1934578x1200700913

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title = "Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii",

abstract = "Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 μg/mL.",

author = "Satoru Yokoyama and Bang, {Tran Hai} and Kuniyoshi Shimizu and Ryuichiro Kondo",

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AB - Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 μg/mL.

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Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii

Abstract

All Science Journal Classification (ASJC) codes

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