TY - GEN
T1 - Optical imaging of plastic changes induced by fear conditioning in the auditory cortex of guinea pig
AU - Ide, Yoshinori
AU - Lauwereyns, Johan
AU - Tsukada, Minoru
PY - 2009
Y1 - 2009
N2 - In this study, the plastic change in the auditory cortex induced by fear conditioning with pairing of sound (Conditioned Stimulus, CS) and electric foot-shock (Unconditioned Stimulus, US) was investigated by using of an optical recording. To investigate the effect of associated learning, optical signals in the auditory cortex to CS (12 kHz pure tone) and non-CS (8 kHz and 16 kHz pure tone) were recorded before and after the conditioning. As a result, the response area only to CS increased after the conditioning. On the other hand, to investigate whether auditory information could be retrieved by electric foot-shock after associated learning or not, auditory response to foot-shock alone was also investigated. As a result, the optical response in the auditory cortex to electric foot-shock alone could not be observed before the conditioning but clearly appeared after the conditioning.
AB - In this study, the plastic change in the auditory cortex induced by fear conditioning with pairing of sound (Conditioned Stimulus, CS) and electric foot-shock (Unconditioned Stimulus, US) was investigated by using of an optical recording. To investigate the effect of associated learning, optical signals in the auditory cortex to CS (12 kHz pure tone) and non-CS (8 kHz and 16 kHz pure tone) were recorded before and after the conditioning. As a result, the response area only to CS increased after the conditioning. On the other hand, to investigate whether auditory information could be retrieved by electric foot-shock after associated learning or not, auditory response to foot-shock alone was also investigated. As a result, the optical response in the auditory cortex to electric foot-shock alone could not be observed before the conditioning but clearly appeared after the conditioning.
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U2 - 10.1007/978-3-642-02490-0_51
DO - 10.1007/978-3-642-02490-0_51
M3 - Conference contribution
AN - SCOPUS:70349094869
SN - 3642024890
SN - 9783642024894
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 416
EP - 422
BT - Advances in Neuro-Information Processing - 15th International Conference, ICONIP 2008, Revised Selected Papers
T2 - 15th International Conference on Neuro-Information Processing, ICONIP 2008
Y2 - 25 November 2008 through 28 November 2008
ER -