TY - GEN
T1 - On-chip cellular force measurement by Direct-Outer-Drive mechanism
AU - Kakio, Tsubasa
AU - Bilal, Turan
AU - Sakuma, Shinya
AU - Kaneko, Makoto
AU - Arai, Fumihito
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - This paper reports a novel on-chip cellular force measurement method of single cells using Direct-Outer-Drive mechanism (D-O-D mechanism). This D-O-D mechanism enables high speed (1 kHz), high power (1 kN) and high accurate manipulation (nanometer-order) of Robochip (Robot-integrated microfluidic chip) and mechanical property measurement of single cells. We succeeded in mechanical property measurement of single animal cells with size of ∼ 15 μm. Furthermore, by adopting flow systems of microfluidic chip, we can achieve a high-speed, high-precision, and high-throughput consecutive cellular force measurement of single flowing cells.
AB - This paper reports a novel on-chip cellular force measurement method of single cells using Direct-Outer-Drive mechanism (D-O-D mechanism). This D-O-D mechanism enables high speed (1 kHz), high power (1 kN) and high accurate manipulation (nanometer-order) of Robochip (Robot-integrated microfluidic chip) and mechanical property measurement of single cells. We succeeded in mechanical property measurement of single animal cells with size of ∼ 15 μm. Furthermore, by adopting flow systems of microfluidic chip, we can achieve a high-speed, high-precision, and high-throughput consecutive cellular force measurement of single flowing cells.
UR - http://www.scopus.com/inward/record.url?scp=84893751536&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893751536&partnerID=8YFLogxK
U2 - 10.1109/MHS.2013.6710424
DO - 10.1109/MHS.2013.6710424
M3 - Conference contribution
AN - SCOPUS:84893751536
SN - 9781479915293
T3 - 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
BT - 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
PB - IEEE Computer Society
T2 - 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
Y2 - 10 November 2013 through 13 November 2013
ER -