TY - GEN
T1 - On-chip cell manipulation by magnetically modified soft microactuators
AU - Yamanishi, Yoko
AU - Sakuma, Shinya
AU - Arai, Fumihito
PY - 2008
Y1 - 2008
N2 - We have developed magnetically modified polymeric soft microactuators in microchip as replacement of conventional manual cell manipulations such as pipetting and centrifugation. In the past papers [1] we have reported novel magnetically driven polymeric microtools for non-intrusive and no contamination experiments on a chip. The main features of them were 1. fabrication of any shape, 2. soft (harmless to cellls) 3. no stiction and 4. mass production at low cost enabling disposability. For the current research, we have demonstrated manipulation of oocyte with produced novel soft microactuators. These magnetic microtools provide a number of functions such as microvalve and microrotor. The potential impact of this technology includes sample preparations, selection and separation, loading and immobilization, genetic operation, tracking, mixing and reaction techniques into portable microfluidic labs-on-a-chip, culture systems.
AB - We have developed magnetically modified polymeric soft microactuators in microchip as replacement of conventional manual cell manipulations such as pipetting and centrifugation. In the past papers [1] we have reported novel magnetically driven polymeric microtools for non-intrusive and no contamination experiments on a chip. The main features of them were 1. fabrication of any shape, 2. soft (harmless to cellls) 3. no stiction and 4. mass production at low cost enabling disposability. For the current research, we have demonstrated manipulation of oocyte with produced novel soft microactuators. These magnetic microtools provide a number of functions such as microvalve and microrotor. The potential impact of this technology includes sample preparations, selection and separation, loading and immobilization, genetic operation, tracking, mixing and reaction techniques into portable microfluidic labs-on-a-chip, culture systems.
UR - http://www.scopus.com/inward/record.url?scp=51649120444&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=51649120444&partnerID=8YFLogxK
U2 - 10.1109/ROBOT.2008.4543319
DO - 10.1109/ROBOT.2008.4543319
M3 - Conference contribution
AN - SCOPUS:51649120444
SN - 9781424416479
T3 - Proceedings - IEEE International Conference on Robotics and Automation
SP - 899
EP - 904
BT - 2008 IEEE International Conference on Robotics and Automation, ICRA 2008
T2 - 2008 IEEE International Conference on Robotics and Automation, ICRA 2008
Y2 - 19 May 2008 through 23 May 2008
ER -