Nuclear matrix association regions of rat α2-macroglobulin gene

Takashi Ito; Yoshiyuki Sakaki

doi:10.1016/0006-291X(87)90388-3

Nuclear matrix association regions of rat α2-macroglobulin gene

Takashi Ito, Yoshiyuki Sakaki

Bioregulation

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

We have identified DNA fragments which bind specifically to the nuclear matrix in vitro, termed matrix association regions (MARs), in the first and fourth introns of rat α₂-macroglobulin gene. The MAR in the first intron is enriched with sequences closely related to the cleavage consensus of topoisomerase II, and contains the binding site of nuclear factor-α, a sequence-specific DNA binding protein reported previously.

Original language	English
Pages (from-to)	449-454
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	149
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(87)90388-3
Publication status	Published - Dec 16 1987

All Science Journal Classification (ASJC) codes

Biochemistry
Biophysics
Molecular Biology

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10.1016/0006-291X(87)90388-3

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title = "Nuclear matrix association regions of rat α2-macroglobulin gene",

abstract = "We have identified DNA fragments which bind specifically to the nuclear matrix in vitro, termed matrix association regions (MARs), in the first and fourth introns of rat α2-macroglobulin gene. The MAR in the first intron is enriched with sequences closely related to the cleavage consensus of topoisomerase II, and contains the binding site of nuclear factor-α, a sequence-specific DNA binding protein reported previously.",

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AB - We have identified DNA fragments which bind specifically to the nuclear matrix in vitro, termed matrix association regions (MARs), in the first and fourth introns of rat α2-macroglobulin gene. The MAR in the first intron is enriched with sequences closely related to the cleavage consensus of topoisomerase II, and contains the binding site of nuclear factor-α, a sequence-specific DNA binding protein reported previously.

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Nuclear matrix association regions of rat α2-macroglobulin gene

Abstract

All Science Journal Classification (ASJC) codes

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