Novel cage-type azaparacyclophane bearing chiral binding sites

Yukito Murakami, Teruhisa Ohno, Osamu Hayashida, Yoshio Hisaeda

    Research output: Contribution to journalArticlepeer-review

    34 Citations (Scopus)


    The guest-binding behaviour of a novel cage-type azaparacyclophane, which has been prepared by the reaction of N,N′,N″,N‴-tetravalyl-1, 6,20,25-tetraaza[]paracyclophane with N,N′,N″,N‴- tetrakis(5-carboxynicotinoyl)-2,11,20,29-tetraaza[]paracyclophane, was examined in aqueous media and evaluated by a computer-aided molecular modelling study on the basis of molecular mechanics (MM2 and MMP2) and molecular dynamics (AMBER and CHARMM) conformational search.

    Original languageEnglish
    Pages (from-to)950-952
    Number of pages3
    JournalJournal of the Chemical Society, Chemical Communications
    Issue number14
    Publication statusPublished - 1991

    All Science Journal Classification (ASJC) codes

    • Molecular Medicine


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