Nonfamilial Prealbumin-Type Amyloid Polyneuropathy

Jun Ochiai, Shozo Tobimatsu, Takuro Kobayashi, Tetsuyuki Kitamoto, Tetsuo Kitaguchi, Hirokazu Furuya, Ikuo Goto, Yoshigoro Kuroiwa

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 53-year-old man with nonfamilial prealbumin-type amyloid polyneuropathy had severe motor, sensory, and autonomic polyneuropathy, beginning at age 48 years. These clinical features closely resembled familial amyloid polyneuropathy (FAP), but abnormal serum prealbumin levels, specific to FAP (Japanese type), were not detected by radioimmunoassay; DNA sequence for prealbumin was normal. Thus, the diagnosis of FAP was excluded. A possible diagnosis of systemic senile amyloidosis was also considered.

Original languageEnglish
Pages (from-to)1294-1295
Number of pages2
JournalArchives of Neurology
Issue number12
Publication statusPublished - Dec 1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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