Nine treated cases of retinoblastoma preserving the eyeglobe

Yoko Fujita, Hiroshi Yoshikawa, Mika Tanabe, Aiko Suminoe, Yuhki Koga, Shigenobu Suzuki, Tatsuro Ishibashi

Research output: Contribution to journalArticlepeer-review


Purpose: To report 9 cases of retinoblastoma treated by conservative means. Cases and Method: This retrospective study was made on 9 cases out of a consecutive series of 41 cases of retinoblastoma treated by us during the past 10 years. The 9 cases comprised 1 unilateral and 8 bilateral cases. Bilateral cases received enucleation of more advanced eye with the fellow eye treated by preserving the eyeglobe. Results: According to the international classification, 5 eyes belonged to group B and 4 eyes to group C. All the 9 cases received systemic chemotherapy and diode laser irradiation. Intravitreal injection of melphalan was additionally performed in 2 cases, plaque radiotherapy in 2 cases, external beam radiotherapy in 2 cases, and selective ophthalmic arterial injection in one case. Visual function was well-preserved in 7 out of the 9 eyes without major complications during the follow-up for 9 to 121 months, average 61 months. Conclusion: All the 5 eyes of retinoblastoma belonging to group B and 3 out of 4 eyes belonging to group C were successfully treated by conservative means without severe side effects.

Original languageEnglish
Pages (from-to)1153-1159
Number of pages7
JournalJapanese Journal of Clinical Ophthalmology
Issue number8
Publication statusPublished - Aug 2012

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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