TY - JOUR
T1 - Nickel-catalyzed formation of a carbon-nitrogen bond at the β position of saturated ketones
AU - Ueno, Satoshi
AU - Shimizu, Ryosuke
AU - Kuwano, Ryoichi
PY - 2009/6/8
Y1 - 2009/6/8
N2 - Gone fishing: When propiophenone and related ethyl ketones are treated with morpholine in the presence of K3PO4, chlorobenzene, and [Ni(cod)2]/PMe3 catalyst, a carbon-nitrogen bond is formed selectively at the β position (see scheme; cod=cycloocta-1,5-diene). Secondary amines were employed as substrates to give the corresponding β- enaminones.
AB - Gone fishing: When propiophenone and related ethyl ketones are treated with morpholine in the presence of K3PO4, chlorobenzene, and [Ni(cod)2]/PMe3 catalyst, a carbon-nitrogen bond is formed selectively at the β position (see scheme; cod=cycloocta-1,5-diene). Secondary amines were employed as substrates to give the corresponding β- enaminones.
UR - http://www.scopus.com/inward/record.url?scp=70349964335&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349964335&partnerID=8YFLogxK
U2 - 10.1002/anie.200900892
DO - 10.1002/anie.200900892
M3 - Article
C2 - 19444844
AN - SCOPUS:70349964335
SN - 1433-7851
VL - 48
SP - 4543
EP - 4545
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 25
ER -