TY - JOUR
T1 - New therapies for controlling atopic itch
AU - Furue, Masutaka
AU - Kadono, Takafumi
N1 - Publisher Copyright:
© 2015 Japanese Dermatological Association.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Chronic itch in atopic dermatitis markedly diminishes the quality of life of affected individuals. Sleep disturbance and impaired productivity in work due to chronic itch impose a socioeconomic burden. Conventional therapies for atopic dermatitis are capable of reducing atopic itch. However, the majority of patients are not satisfied with the antipruritic capacity of conventional treatments. In this review, we summarize recent progress in itch signaling in the skin, dorsal root ganglion and spinal cord. New therapies for controlling atopic itch are also discussed.
AB - Chronic itch in atopic dermatitis markedly diminishes the quality of life of affected individuals. Sleep disturbance and impaired productivity in work due to chronic itch impose a socioeconomic burden. Conventional therapies for atopic dermatitis are capable of reducing atopic itch. However, the majority of patients are not satisfied with the antipruritic capacity of conventional treatments. In this review, we summarize recent progress in itch signaling in the skin, dorsal root ganglion and spinal cord. New therapies for controlling atopic itch are also discussed.
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U2 - 10.1111/1346-8138.13060
DO - 10.1111/1346-8138.13060
M3 - Review article
C2 - 26332459
AN - SCOPUS:84940944932
SN - 0385-2407
VL - 42
SP - 847
EP - 850
JO - Journal of Dermatology
JF - Journal of Dermatology
IS - 9
ER -