TY - GEN
T1 - New nanocomposite biomaterials controlling surface and bulk properties using supercritical carbon dioxide
AU - Hoshi, Tora
AU - Sawagushi, Takashi
AU - Matsuno, Ryosuke
AU - Konno, Tomohiro
AU - Takai, Madoka
AU - Ishihara, Kazuhiko
PY - 2008
Y1 - 2008
N2 - The molecular composite composed of polyethylene (PE) and polyvinyl acetate) (PVAc) prepared using supercritical carbon dioxide (scCO2) and its surface modification for biocompatible surface demonstrated the creation of novel polymer biomaterials. In this study, this modification process was applied to the PE narrow tube (inside diameter: 300μm, outside diameter: 600μm, length: 5m) It was confirmed that PVAc was uniformly generated in PE tube by infrared imaging measurement of cross-section. After the acetyl group on the surface was hydrolyzed, phospholipid polymer was immobilized to the hydroxyl group on the surface of the tube. The phospholipid polymer immobilized surface showed a drastic reduction in protein adsorption. The surface of the minute and slender tube can be effectively modified using the feature of carbon dioxide whose surface tension is near zero. The modification technology by scCO2 is a promising for creation of variously-shaped new biomaterials.
AB - The molecular composite composed of polyethylene (PE) and polyvinyl acetate) (PVAc) prepared using supercritical carbon dioxide (scCO2) and its surface modification for biocompatible surface demonstrated the creation of novel polymer biomaterials. In this study, this modification process was applied to the PE narrow tube (inside diameter: 300μm, outside diameter: 600μm, length: 5m) It was confirmed that PVAc was uniformly generated in PE tube by infrared imaging measurement of cross-section. After the acetyl group on the surface was hydrolyzed, phospholipid polymer was immobilized to the hydroxyl group on the surface of the tube. The phospholipid polymer immobilized surface showed a drastic reduction in protein adsorption. The surface of the minute and slender tube can be effectively modified using the feature of carbon dioxide whose surface tension is near zero. The modification technology by scCO2 is a promising for creation of variously-shaped new biomaterials.
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U2 - 10.1557/proc-1097-gg04-15
DO - 10.1557/proc-1097-gg04-15
M3 - Conference contribution
AN - SCOPUS:70350289827
SN - 9781605608525
T3 - Materials Research Society Symposium Proceedings
SP - 58
EP - 64
BT - Mechanical Behavior of Biological Materials and Biomaterials
PB - Materials Research Society
T2 - 2008 MRS Spring Meeting
Y2 - 24 March 2008 through 28 March 2008
ER -