Nanobiotechnology: Quantum dots in bioimaging

Yong Zhang, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Contribution to journalReview articlepeer-review

25 Citations (Scopus)


Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.

Original languageEnglish
Pages (from-to)565-572
Number of pages8
JournalExpert Review of Proteomics
Issue number4
Publication statusPublished - Aug 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology


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