Nano-dynamics of living cell surface by AFM

Takaharu Okajima; Masaru Tanaka; Shusaku Tsukiyama; Sadaaki Yamamoto; Masatsugu Shimomura; Hiroshi Tokumoto

Nano-dynamics of living cell surface by AFM

Takaharu Okajima, Masaru Tanaka, Shusaku Tsukiyama, Sadaaki Yamamoto, Masatsugu Shimomura, Hiroshi Tokumoto

Research output: Contribution to conference › Paper › peer-review

Abstract

Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.

Original language	English
Pages	2109
Number of pages	1
Publication status	Published - 2006
Externally published	Yes
Event	55th SPSJ Annual Meeting - Nagoya, Japan Duration: May 24 2006 → May 26 2006

Other

Other	55th SPSJ Annual Meeting
Country/Territory	Japan
City	Nagoya
Period	5/24/06 → 5/26/06

All Science Journal Classification (ASJC) codes

Engineering(all)

Cite this

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title = "Nano-dynamics of living cell surface by AFM",

abstract = "Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.",

author = "Takaharu Okajima and Masaru Tanaka and Shusaku Tsukiyama and Sadaaki Yamamoto and Masatsugu Shimomura and Hiroshi Tokumoto",

year = "2006",

language = "English",

pages = "2109",

note = "55th SPSJ Annual Meeting ; Conference date: 24-05-2006 Through 26-05-2006",

}

TY - CONF

T1 - Nano-dynamics of living cell surface by AFM

AU - Okajima, Takaharu

AU - Tanaka, Masaru

AU - Tsukiyama, Shusaku

AU - Yamamoto, Sadaaki

AU - Shimomura, Masatsugu

AU - Tokumoto, Hiroshi

PY - 2006

Y1 - 2006

N2 - Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.

AB - Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.

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M3 - Paper

AN - SCOPUS:33749822730

SP - 2109

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Nano-dynamics of living cell surface by AFM

Abstract

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All Science Journal Classification (ASJC) codes

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