TY - JOUR
T1 - Multiple roles of Equarin during lens development
AU - Song, Xiaohong
AU - Tanaka, Hideaki
AU - Ohta, Kunimasa
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/4
Y1 - 2014/4
N2 - Since the days of Hans Spemann, the ocular lens has served as one of the most important developmental systems for elucidating the fundamental processes of induction and differentiation. Lens is an important source of signals that influence the eye development and a variety of genes expressed by the lens have been identified. The identification of additional molecule(s), especially secreted ones that might mediate signals, will extend our knowledge of the molecular mechanisms of eye and lens development. Here, we will introduce a soluble molecule, Equarin, and discuss its vital role in multiple aspects of lens development.
AB - Since the days of Hans Spemann, the ocular lens has served as one of the most important developmental systems for elucidating the fundamental processes of induction and differentiation. Lens is an important source of signals that influence the eye development and a variety of genes expressed by the lens have been identified. The identification of additional molecule(s), especially secreted ones that might mediate signals, will extend our knowledge of the molecular mechanisms of eye and lens development. Here, we will introduce a soluble molecule, Equarin, and discuss its vital role in multiple aspects of lens development.
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U2 - 10.1111/dgd.12121
DO - 10.1111/dgd.12121
M3 - Review article
C2 - 24673466
AN - SCOPUS:84898059552
SN - 0012-1592
VL - 56
SP - 199
EP - 205
JO - Development Growth and Differentiation
JF - Development Growth and Differentiation
IS - 3
ER -