MR imaging of renal cell carcinoma: Its role in determining cell type

Kengo Yoshimitsu, Hiroyuki Irie, Tsuyoshi Tajima, Akihiro Nishie, Yoshiki Asayama, Masakazu Hirakawa, Tomohiro Nakayama, Daisuke Kakihara, Hiroshi Honda

Research output: Contribution to journalReview articlepeer-review

49 Citations (Scopus)


Chemical shift gradient-echo MR imaging (CSI) can detect a small amount of fat as signal loss on opposed-phase images as compared with in-phase images. Cytoplasmic fat in clear cell renal cell carcinoma (RCC) or interstitial histiocytic fat in papillary cell RCC can be successfully demonstrated by this technique. T2*-weighted gradient-echo or echo-planar MR imaging can detect local susceptibility, for example, due to cytoplasmic or interstitial histiocytic hemosiderin deposition in papillary cell RCC. CSI can also show this focal susceptibility as excessive signal loss on in-phase images as compared with opposed-phase images. MR imaging can thus help predict the cell types (clear cell and papillary cell) of RCC. These findings may be important in the decision-making process in the management of patients with suspected RCC, particularly those who are not indicated for radical surgery.

Original languageEnglish
Pages (from-to)371-376
Number of pages6
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Issue number6
Publication statusPublished - Nov 2004

All Science Journal Classification (ASJC) codes

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology


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