TY - JOUR
T1 - Monopolar flocking of microtubules in collective motion
AU - Afroze, Farhana
AU - Inoue, Daisuke
AU - Farhana, Tamanna Ishrat
AU - Hiraiwa, Tetsuya
AU - Akiyama, Ryo
AU - Kabir, Arif Md Rashedul
AU - Sada, Kazuki
AU - Kakugo, Akira
N1 - Funding Information:
This work is supported by JSPS KAKENHI grant number 20K15141 (to D.I), JP16K17777 , JP19K03764 (to T.H), JP19H01863 , JP19K03772 , JP18K03555 , JP16K05512 (to R.A) and JP18H03673 (to A.K); Mechanobiology Institute, National University of Singapore , (to T.H); a research grant from Hirose Foundation to A.M.R.K ( PK22201017 ); a Grant-in-Aid for Scientific Research on Innovative Areas “Molecular Engine” ( JSPS KAKENHI Grant Number JP18H05423 ), a Grant-in-Aid for JSPS Research Fellows ( 18F18323 ) and New Energy and Industrial Technology Development Organization (NEDO) ( JPNP20006 ) (to A.K); “ Leading Initiative for Excellent Young Researchers (LEADER) ” ( JSPS Grant number RAHJ290002 ), Kazato Research Encouragement Prize and Nikki-Saneyoshi Scholarship Foundation Grant (to D.I).
Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2021/7/23
Y1 - 2021/7/23
N2 - Flocking is a fascinating coordinated behavior of living organisms or self-propelled particles (SPPs). Particularly, monopolar flocking has been attractive due to its potential applications in various fields. However, the underlying mechanism behind flocking and emergence of monopolar motion in flocking of SPPs has remained obscured. Here, we demonstrate monopolar flocking of kinesin-driven microtubules, a self-propelled biomolecular motor system. Microtubules with an intrinsic structural chirality preferentially move towards counter-clockwise direction. At high density, the CCW motion of microtubules facilitates monopolar flocking and formation of a spiral pattern. The monopolar flocking of microtubules is accounted for by a torque generated when the motion of microtubules was obstructed due to collisions. Our results shed light on flocking and emergence of monopolar motion in flocking of chiral active matters. This work will help regulate the polarity in collective motion of SPPs which in turn will widen their applications in nanotechnology, materials science and engineering.
AB - Flocking is a fascinating coordinated behavior of living organisms or self-propelled particles (SPPs). Particularly, monopolar flocking has been attractive due to its potential applications in various fields. However, the underlying mechanism behind flocking and emergence of monopolar motion in flocking of SPPs has remained obscured. Here, we demonstrate monopolar flocking of kinesin-driven microtubules, a self-propelled biomolecular motor system. Microtubules with an intrinsic structural chirality preferentially move towards counter-clockwise direction. At high density, the CCW motion of microtubules facilitates monopolar flocking and formation of a spiral pattern. The monopolar flocking of microtubules is accounted for by a torque generated when the motion of microtubules was obstructed due to collisions. Our results shed light on flocking and emergence of monopolar motion in flocking of chiral active matters. This work will help regulate the polarity in collective motion of SPPs which in turn will widen their applications in nanotechnology, materials science and engineering.
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U2 - 10.1016/j.bbrc.2021.05.037
DO - 10.1016/j.bbrc.2021.05.037
M3 - Article
C2 - 34062389
AN - SCOPUS:85107028393
SN - 0006-291X
VL - 563
SP - 73
EP - 78
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
ER -