Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study

V. Meenakumari; A. Milton Franklin Benial; Kazuhiro Ichikawa; Ken Ichi Yamada; A. Jawahar; Hideo Utsumi

doi:10.1063/1.4791356

Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study

V. Meenakumari, A. Milton Franklin Benial, Kazuhiro Ichikawa, Ken Ichi Yamada, A. Jawahar, Hideo Utsumi

Molecular Bioinformatics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of ¹⁴N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T_2e) decreases with increasing concentration. The isotropic g-values were obtained.

Original language	English
Title of host publication	Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012
Pages	952-953
Number of pages	2
DOIs	https://doi.org/10.1063/1.4791356
Publication status	Published - 2013
Event	57th DAE Solid State Physics Symposium 2012 - Bombay, Mumbai, India Duration: Dec 3 2012 → Dec 7 2012

Publication series

Name	AIP Conference Proceedings
Volume	1512
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Other

Other	57th DAE Solid State Physics Symposium 2012
Country/Territory	India
City	Bombay, Mumbai
Period	12/3/12 → 12/7/12

All Science Journal Classification (ASJC) codes

General Physics and Astronomy

Access to Document

10.1063/1.4791356

Cite this

Meenakumari, V., Benial, A. M. F., Ichikawa, K., Yamada, K. I., Jawahar, A., & Utsumi, H. (2013). Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. In Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012 (pp. 952-953). (AIP Conference Proceedings; Vol. 1512). https://doi.org/10.1063/1.4791356

Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. / Meenakumari, V.; Benial, A. Milton Franklin; Ichikawa, Kazuhiro et al.
Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. 2013. p. 952-953 (AIP Conference Proceedings; Vol. 1512).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Meenakumari, V, Benial, AMF, Ichikawa, K, Yamada, KI, Jawahar, A & Utsumi, H 2013, Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. in Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. AIP Conference Proceedings, vol. 1512, pp. 952-953, 57th DAE Solid State Physics Symposium 2012, Bombay, Mumbai, India, 12/3/12. https://doi.org/10.1063/1.4791356

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abstract = "Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.",

author = "V. Meenakumari and Benial, \{A. Milton Franklin\} and Kazuhiro Ichikawa and Yamada, \{Ken Ichi\} and A. Jawahar and Hideo Utsumi",

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N2 - Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.

AB - Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.

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Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study

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