Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions

Seiji Shinkai; Masayuki Takeuchi

doi:10.1016/j.bios.2004.03.036

Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions

Seiji Shinkai, Masayuki Takeuchi

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

Original language	English
Pages (from-to)	1250-1259
Number of pages	10
Journal	Biosensors and Bioelectronics
Volume	20
Issue number	6
DOIs	https://doi.org/10.1016/j.bios.2004.03.036
Publication status	Published - Dec 15 2004
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biotechnology
Biophysics
Biomedical Engineering
Electrochemistry

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10.1016/j.bios.2004.03.036

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title = "Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions",

abstract = "Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.",

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AU - Takeuchi, Masayuki

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N2 - Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

AB - Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

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JO - Biosensors and Bioelectronics

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ER -

Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions

Abstract

All Science Journal Classification (ASJC) codes

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