Molecular design and synthesis of a biscalix[4]arene-based cage molecule

Koji Araki, Koichi Sisido, Katsuya Hisaichi, Seiji Shinkai

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


The biscalixarene-based cage molecule, the synthesis of which is precedented but only in "very low yield", was designed on the basis of the careful assessment of the reaction route and molecular models and synthesized for the first time in reasonable yield.

Original languageEnglish
Pages (from-to)8297-8300
Number of pages4
JournalTetrahedron Letters
Issue number51
Publication statusPublished - Dec 17 1993
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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