TY - JOUR
T1 - Molecular Cloning of the Smaller Subunit (P52) of Rat Liver Mitochondrial Processing Protease
AU - Kitada, Sakae
AU - Niidome, Takuro
AU - Nagano, Takashi
AU - Ogishima, Tadashi
AU - Ito, Akio
PY - 1993/1/1
Y1 - 1993/1/1
N2 - A cDNA encoding the smaller subunit (P52) of mitochondrial processing protease was isolated from a rat liver cDNA library, using cDNA fragment for yeast MAS1 as the probe. The deduced amino acid sequence is highly homologous to those of PEP from Neurospora crassa and MAS1 from Saccharomyces cerevisiae. After in vitro transcription and translation, the precursor peptide was imported into isolated rat liver mitochondria and processed to its mature form.
AB - A cDNA encoding the smaller subunit (P52) of mitochondrial processing protease was isolated from a rat liver cDNA library, using cDNA fragment for yeast MAS1 as the probe. The deduced amino acid sequence is highly homologous to those of PEP from Neurospora crassa and MAS1 from Saccharomyces cerevisiae. After in vitro transcription and translation, the precursor peptide was imported into isolated rat liver mitochondria and processed to its mature form.
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U2 - 10.1006/bbrc.1993.1044
DO - 10.1006/bbrc.1993.1044
M3 - Article
C2 - 8422255
AN - SCOPUS:0027267627
SN - 0006-291X
VL - 190
SP - 289
EP - 293
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 1
ER -