Molecular biology of the natriuretic peptide system

Y. Ogawa, K. Nakao, H. Itoh, S. Suga, H. Imura

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


The natriuretic peptide system is composed of at least three distinct endogenous peptides: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), and three receptors: ANP-A receptor/GC-A, ANP-B receptor/GC-B and the clearance receptor. This system influences the control of body fluid and blood pressure as cardiac hormones and local regulators. Recent advances in molecular biology have unravel the molecular mechanism of the natriuretic peptide system and have facilitated our understanding of it. The present review gives the current knowledge of the molecular biology of the natriuretic peptide system.

Original languageEnglish
Pages (from-to)2885-2892
Number of pages8
JournalNippon rinsho. Japanese journal of clinical medicine
Issue number12
Publication statusPublished - Dec 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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