MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Toshihiro Ito; Toyohiro Naito; Hikari Terada; Yoichi Otsuka; Niko Kimura; Noritada Kaji

MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Toshihiro Ito, Toyohiro Naito, Hikari Terada, Yoichi Otsuka, Niko Kimura, Noritada Kaji

Functional Materials Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this study, we have developed microwell array devices for phospholipids imaging by scanning probe electrospray ionization mass spectrometry (SPESI-MS) at a single cell level. With a combination of the microwell array devices for single-cell isolation and collection and SPESI-MS, we successfully obtained phospholipids mass information from the surface of a single cell with high spatial resolution. The devices have a great potential as a new platform for single-cell mass spectrometry imaging.

Original language	English
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	593-594
Number of pages	2
ISBN (Electronic)	9781733419031
Publication status	Published - 2021
Event	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States Duration: Oct 10 2021 → Oct 14 2021

Publication series

Name	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/Territory	United States
City	Palm Springs, Virtual
Period	10/10/21 → 10/14/21

All Science Journal Classification (ASJC) codes

Bioengineering
Chemical Engineering (miscellaneous)

Cite this

Ito, T., Naito, T., Terada, H., Otsuka, Y., Kimura, N., & Kaji, N. (2021). MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 593-594). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY. / Ito, Toshihiro; Naito, Toyohiro; Terada, Hikari et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 593-594 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ito, T, Naito, T, Terada, H, Otsuka, Y, Kimura, N & Kaji, N 2021, MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 593-594, 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, Palm Springs, Virtual, United States, 10/10/21.

Ito T, Naito T, Terada H, Otsuka Y, Kimura N, Kaji N. MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2021. p. 593-594. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Ito, Toshihiro ; Naito, Toyohiro ; Terada, Hikari et al. / MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 593-594 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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abstract = "In this study, we have developed microwell array devices for phospholipids imaging by scanning probe electrospray ionization mass spectrometry (SPESI-MS) at a single cell level. With a combination of the microwell array devices for single-cell isolation and collection and SPESI-MS, we successfully obtained phospholipids mass information from the surface of a single cell with high spatial resolution. The devices have a great potential as a new platform for single-cell mass spectrometry imaging.",

author = "Toshihiro Ito and Toyohiro Naito and Hikari Terada and Yoichi Otsuka and Niko Kimura and Noritada Kaji",

note = "Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",

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AU - Kimura, Niko

AU - Kaji, Noritada

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AB - In this study, we have developed microwell array devices for phospholipids imaging by scanning probe electrospray ionization mass spectrometry (SPESI-MS) at a single cell level. With a combination of the microwell array devices for single-cell isolation and collection and SPESI-MS, we successfully obtained phospholipids mass information from the surface of a single cell with high spatial resolution. The devices have a great potential as a new platform for single-cell mass spectrometry imaging.

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T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021

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ER -

MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Abstract

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Conference

All Science Journal Classification (ASJC) codes

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