Mice deficient in γδ T cells are resistant to lethal infection with Salmonella choleraesuis

M. Emoto, H. Nishimura, T. Sakai, K. Hiromatsu, H. Gomi, S. Itohara, Y. Yoshikai

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Mice deficient in γδ T cells were resistant to the gram-negative bacteremic sepsis caused by infection with a high dose of Salmonella choleraesuis accompanied by impaired tumor necrosis factor alpha production in vivo and in vitro. γδ T cells may play a role in the pathogenesis of lethal infection with S. choleraesuis.

Original languageEnglish
Pages (from-to)3736-3738
Number of pages3
JournalInfection and Immunity
Volume63
Issue number9
DOIs
Publication statusPublished - 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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