Metal-oxide nanowire molecular sensors and their promises

Hao Zeng, Guozhu Zhang, Kazuki Nagashima, Tsunaki Takahashi, Takuro Hosomi, Takeshi Yanagida

Research output: Contribution to journalReview articlepeer-review

28 Citations (Scopus)


During the past two decades, one-dimensional (1D) metal-oxide nanowire (NW)-based molecular sensors have been witnessed as promising candidates to electrically detect volatile organic compounds (VOCs) due to their high surface to volume ratio, single crystallinity, and well-defined crystal orientations. Furthermore, these unique physical/chemical features allow the integrated sensor electronics to work with a long-term stability, ultra-low power consumption, and miniature device size, which promote the fast development of “trillion sensor electronics” for Internet of things (IoT) applications. This review gives a comprehensive overview of the recent studies and achievements in 1D metal-oxide nanowire synthesis, sensor device fabrication, sensing material functionalization, and sensing mechanisms. In addition, some critical issues that impede the practical application of the 1D metal-oxide nanowire-based sensor electronics, including selectivity, long-term stability, and low power consumption, will be highlighted. Finally, we give a prospective account of the remaining issues toward the laboratory-to-market transformation of the 1D nanostructure-based sensor electronics.

Original languageEnglish
Article number41
Pages (from-to)1-41
Number of pages41
Issue number2
Publication statusPublished - Feb 2021

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Physical and Theoretical Chemistry


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