Mesenteric panniculitis of the colon - Review of the literature and report of two cases

Yosuke Adachi, Masaki Mori, Munetomo Enjoji, Hiroaki Ueo, Keizo Sugimachi

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)


Eighteen cases of mesenteric panniculitis of the colon collected from the literature, together with two cases from the authors' source, were reviewed. The disease occurred most often in late adult life, with a male predominance. Symptoms were abdominal pain, diarrhea, constipation, and a lower abdominal mass in most patients. Barium enema disclosed narrowing, shortening, and poor extensibility of the colon, and ultrasonography and computed tomography showed thickening of the mesocolon and colonic wall with soft-tissue density. Exploratory laparotomy was done in all patients, and colectomy, colostomy, or other surgical treatments were performed in 17 (85 percent). Gross appearance at the time of surgery was characterized by a marked thickening or a firm mass of the mesocolon with a puckered surface involving the appendices epiploicae of the colon. Microscopically, degeneration of the adipose tissue, revealed by aggregates of lipid-laden macrophages, was diagnostic. Inflammatory infiltration and fibrosis also were present in many patients. Mesenteric panniculitis of the colon seems to be a lesion more advaced than the same condition of the small intestine, and colostomy or bypass surgery may be needed for alleviation of severe symptoms.

Original languageEnglish
Pages (from-to)962-966
Number of pages5
JournalDiseases of the Colon & Rectum
Issue number12
Publication statusPublished - Dec 1987
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Gastroenterology


Dive into the research topics of 'Mesenteric panniculitis of the colon - Review of the literature and report of two cases'. Together they form a unique fingerprint.

Cite this