Mechanical immobilization of Hela cells on aligned carbon nanotube array

Hiroki Ago; Ei ichiro Uchimura; Takeshi Saito; Satoshi Ohshima; Naoki Ishigami; Masaharu Tsuji; Motoo Yumura; Masato Miyake

doi:10.1016/j.matlet.2006.03.151

Mechanical immobilization of Hela cells on aligned carbon nanotube array

Hiroki Ago, Ei ichiro Uchimura, Takeshi Saito, Satoshi Ohshima, Naoki Ishigami, Masaharu Tsuji, Motoo Yumura, Masato Miyake

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We demonstrate that an aligned multi-walled carbon nanotube array can immobilize Hela cells through insertion of the nanotube tips into the cell. The cells were immobilized by pressing onto the nanotube array with the aid of mild centrifugal force. The nanotube array fixed a much larger number of cells compared with the flat surface of a Si substrate, indicating strong binding force of the aligned nanotubes toward the cell. This is the first example of mechanical cell immobilization, which offers future applications of the nanotube array for cellular biology, tissue engineering, and biomolecular devices.

Original language	English
Pages (from-to)	3851-3854
Number of pages	4
Journal	Materials Letters
Volume	60
Issue number	29-30
DOIs	https://doi.org/10.1016/j.matlet.2006.03.151
Publication status	Published - Dec 2006

All Science Journal Classification (ASJC) codes

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2006.03.151

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title = "Mechanical immobilization of Hela cells on aligned carbon nanotube array",

abstract = "We demonstrate that an aligned multi-walled carbon nanotube array can immobilize Hela cells through insertion of the nanotube tips into the cell. The cells were immobilized by pressing onto the nanotube array with the aid of mild centrifugal force. The nanotube array fixed a much larger number of cells compared with the flat surface of a Si substrate, indicating strong binding force of the aligned nanotubes toward the cell. This is the first example of mechanical cell immobilization, which offers future applications of the nanotube array for cellular biology, tissue engineering, and biomolecular devices.",

author = "Hiroki Ago and Uchimura, {Ei ichiro} and Takeshi Saito and Satoshi Ohshima and Naoki Ishigami and Masaharu Tsuji and Motoo Yumura and Masato Miyake",

note = "Funding Information: This work is supported by Nano-Carbon Technology (NCT) Project of NEDO, CREST–JST, and Joint Project of Chemical Synthesis Core Research Institutions. HA acknowledges the support from Industrial Technology Research Program in 2005 from NEDO. Authors thank Ms. A. Maehara for the experimental help and Dr. K. Matsuura for helpful discussion.",

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doi = "10.1016/j.matlet.2006.03.151",

language = "English",

volume = "60",

pages = "3851--3854",

journal = "Materials Letters",

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publisher = "Elsevier",

number = "29-30",

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TY - JOUR

T1 - Mechanical immobilization of Hela cells on aligned carbon nanotube array

AU - Ago, Hiroki

AU - Uchimura, Ei ichiro

AU - Saito, Takeshi

AU - Ohshima, Satoshi

AU - Ishigami, Naoki

AU - Tsuji, Masaharu

AU - Yumura, Motoo

AU - Miyake, Masato

N1 - Funding Information: This work is supported by Nano-Carbon Technology (NCT) Project of NEDO, CREST–JST, and Joint Project of Chemical Synthesis Core Research Institutions. HA acknowledges the support from Industrial Technology Research Program in 2005 from NEDO. Authors thank Ms. A. Maehara for the experimental help and Dr. K. Matsuura for helpful discussion.

PY - 2006/12

Y1 - 2006/12

N2 - We demonstrate that an aligned multi-walled carbon nanotube array can immobilize Hela cells through insertion of the nanotube tips into the cell. The cells were immobilized by pressing onto the nanotube array with the aid of mild centrifugal force. The nanotube array fixed a much larger number of cells compared with the flat surface of a Si substrate, indicating strong binding force of the aligned nanotubes toward the cell. This is the first example of mechanical cell immobilization, which offers future applications of the nanotube array for cellular biology, tissue engineering, and biomolecular devices.

AB - We demonstrate that an aligned multi-walled carbon nanotube array can immobilize Hela cells through insertion of the nanotube tips into the cell. The cells were immobilized by pressing onto the nanotube array with the aid of mild centrifugal force. The nanotube array fixed a much larger number of cells compared with the flat surface of a Si substrate, indicating strong binding force of the aligned nanotubes toward the cell. This is the first example of mechanical cell immobilization, which offers future applications of the nanotube array for cellular biology, tissue engineering, and biomolecular devices.

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DO - 10.1016/j.matlet.2006.03.151

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VL - 60

SP - 3851

EP - 3854

JO - Materials Letters

JF - Materials Letters

IS - 29-30

ER -

Mechanical immobilization of Hela cells on aligned carbon nanotube array

Abstract

All Science Journal Classification (ASJC) codes

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