Mechanical characterization system using on-chip probe with wide range actuation

Keitaro Ito; Shinya Sakuma; Masaki Kimura; Takanori Takebe; Makoto Kaneko; Fumihito Arai

doi:10.1109/MHS.2016.7824204

Mechanical characterization system using on-chip probe with wide range actuation

Keitaro Ito, Shinya Sakuma, Masaki Kimura, Takanori Takebe, Makoto Kaneko, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

In this paper, we focus on mechanical characterization of human umbilical vein endothelial cell(HUVEC) and mesenchymal stem cell(MSC) co-cultured spheroids. HUVEC/MSC co-cultured spheroid has a characteristic that the size becomes compact with culture day increase. In order to measure the mechanical characteristics of size changing spheroids, we apply whole chip deformation mechanism to the actuation method of on-chip probes for wide range actuation. Finally, we evaluate the stiffness of spheroids by using stiffness-index.

Original language	English
Title of host publication	2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781509027842
DOIs	https://doi.org/10.1109/MHS.2016.7824204
Publication status	Published - Jan 18 2017
Externally published	Yes
Event	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 - Nagoya, Japan Duration: Nov 28 2016 → Nov 30 2016

Publication series

Name	2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

Other

Other	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
Country/Territory	Japan
City	Nagoya
Period	11/28/16 → 11/30/16

All Science Journal Classification (ASJC) codes

Medicine (miscellaneous)
Biomedical Engineering
Mechanical Engineering
Human-Computer Interaction
Instrumentation
Computer Science Applications
Biotechnology
Artificial Intelligence

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/MHS.2016.7824204

Cite this

Ito, K., Sakuma, S., Kimura, M., Takebe, T., Kaneko, M., & Arai, F. (2017). Mechanical characterization system using on-chip probe with wide range actuation. In 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 Article 7824204 (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2016.7824204

Mechanical characterization system using on-chip probe with wide range actuation. / Ito, Keitaro; Sakuma, Shinya; Kimura, Masaki et al.
2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc., 2017. 7824204 (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ito, K, Sakuma, S, Kimura, M, Takebe, T, Kaneko, M & Arai, F 2017, Mechanical characterization system using on-chip probe with wide range actuation. in 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016., 7824204, 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, Institute of Electrical and Electronics Engineers Inc., 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, Nagoya, Japan, 11/28/16. https://doi.org/10.1109/MHS.2016.7824204

Ito K, Sakuma S, Kimura M, Takebe T, Kaneko M, Arai F. Mechanical characterization system using on-chip probe with wide range actuation. In 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc. 2017. 7824204. (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016). doi: 10.1109/MHS.2016.7824204

Ito, Keitaro ; Sakuma, Shinya ; Kimura, Masaki et al. / Mechanical characterization system using on-chip probe with wide range actuation. 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc., 2017. (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016).

@inproceedings{6a84822eac5a41599a28d77bf9b24d51,

title = "Mechanical characterization system using on-chip probe with wide range actuation",

abstract = "In this paper, we focus on mechanical characterization of human umbilical vein endothelial cell(HUVEC) and mesenchymal stem cell(MSC) co-cultured spheroids. HUVEC/MSC co-cultured spheroid has a characteristic that the size becomes compact with culture day increase. In order to measure the mechanical characteristics of size changing spheroids, we apply whole chip deformation mechanism to the actuation method of on-chip probes for wide range actuation. Finally, we evaluate the stiffness of spheroids by using stiffness-index.",

author = "Keitaro Ito and Shinya Sakuma and Masaki Kimura and Takanori Takebe and Makoto Kaneko and Fumihito Arai",

note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 ; Conference date: 28-11-2016 Through 30-11-2016",

year = "2017",

month = jan,

day = "18",

doi = "10.1109/MHS.2016.7824204",

language = "English",

series = "2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016",

address = "United States",

}

TY - GEN

T1 - Mechanical characterization system using on-chip probe with wide range actuation

AU - Ito, Keitaro

AU - Sakuma, Shinya

AU - Kimura, Masaki

AU - Takebe, Takanori

AU - Kaneko, Makoto

AU - Arai, Fumihito

PY - 2017/1/18

Y1 - 2017/1/18

N2 - In this paper, we focus on mechanical characterization of human umbilical vein endothelial cell(HUVEC) and mesenchymal stem cell(MSC) co-cultured spheroids. HUVEC/MSC co-cultured spheroid has a characteristic that the size becomes compact with culture day increase. In order to measure the mechanical characteristics of size changing spheroids, we apply whole chip deformation mechanism to the actuation method of on-chip probes for wide range actuation. Finally, we evaluate the stiffness of spheroids by using stiffness-index.

AB - In this paper, we focus on mechanical characterization of human umbilical vein endothelial cell(HUVEC) and mesenchymal stem cell(MSC) co-cultured spheroids. HUVEC/MSC co-cultured spheroid has a characteristic that the size becomes compact with culture day increase. In order to measure the mechanical characteristics of size changing spheroids, we apply whole chip deformation mechanism to the actuation method of on-chip probes for wide range actuation. Finally, we evaluate the stiffness of spheroids by using stiffness-index.

UR - http://www.scopus.com/inward/record.url?scp=85013679982&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85013679982&partnerID=8YFLogxK

U2 - 10.1109/MHS.2016.7824204

DO - 10.1109/MHS.2016.7824204

M3 - Conference contribution

AN - SCOPUS:85013679982

T3 - 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

BT - 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

Y2 - 28 November 2016 through 30 November 2016

ER -

Mechanical characterization system using on-chip probe with wide range actuation

Abstract

Publication series

Other

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this