Material-driven fibronectin fibrillogenesis

Marco Cantini, Cristina González-García, Virginia Llopis-Hernández, Manuel Salmerón-Sánchez

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)


Material-driven fibronectin fibrillogenesis is a novel route to engineer the network structure and biological activity of fibronectin fibrillar matrices in analogy with their physiological cell-mediated assembly. We identify specific surface chemistries that promote the cell-free formation of physiological-like fibronectin fibrils in a time- and concentration-dependent process. Our most recent and relevant results, reviewed in the chapter, demonstrate the role of this material-induced fibrillogenesis in cell adhesion, extracellular matrix organization and degradation, and cell differentiation.

Original languageEnglish
Title of host publicationProteins at Interfaces III State of the Art
PublisherAmerican Chemical Society
Number of pages26
ISBN (Print)9780841227965
Publication statusPublished - Dec 12 2012
Externally publishedYes

Publication series

NameACS Symposium Series
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering


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