TY - JOUR
T1 - Manipulation of cell membrane using carbon nanotube scaffold as a photoresponsive stimuli generator
AU - Sada, Takao
AU - Fujigaya, Tsuyohiko
AU - Nakashima, Naotoshi
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2014/8/1
Y1 - 2014/8/1
N2 - We describe, for the first time, the perforation of the cell membrane in the targeted single cell based on the nanosecond pulsed near-infrared (NIR) laser irradiation of a thin film of carbon nanotubes that act as an effective photon absorber as well as stimuli generator. When the power of NIR laser is over 17.5 μJ/pulse, the cell membrane after irradiation is irreversibly disrupted and results in cell death. In sharp contrast, the perforation of the cell membrane occurs at suitable laser power (∼15 μJ/pulse) without involving cell termination.
AB - We describe, for the first time, the perforation of the cell membrane in the targeted single cell based on the nanosecond pulsed near-infrared (NIR) laser irradiation of a thin film of carbon nanotubes that act as an effective photon absorber as well as stimuli generator. When the power of NIR laser is over 17.5 μJ/pulse, the cell membrane after irradiation is irreversibly disrupted and results in cell death. In sharp contrast, the perforation of the cell membrane occurs at suitable laser power (∼15 μJ/pulse) without involving cell termination.
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U2 - 10.1088/1468-6996/15/4/045002
DO - 10.1088/1468-6996/15/4/045002
M3 - Article
AN - SCOPUS:84940327674
SN - 1468-6996
VL - 15
JO - Science and Technology of Advanced Materials
JF - Science and Technology of Advanced Materials
IS - 4
M1 - 045002
ER -