Mammalian cell mutants of membrane phlospholipid biogenesis

Masahiro Nishijima, Osamu Kuge, Kentaro Hanada

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


Cultured mammalian cell mutants defective in the biosynthesis of membrane phospholipids, although limited in number, are increasing our understanding of the molecular mechanisms underlying the biogenesis and the biological significance of membrane phospholipids in higher eukaryotes. This review summarizes the progress in the isolation and characterization of such mutants, focusing on those isolated from cultured Chinese hamster ovary (CHO) cells.

Original languageEnglish
Pages (from-to)324-329
Number of pages6
JournalTrends in Cell Biology
Issue number8
Publication statusPublished - Aug 1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cell Biology


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