TY - JOUR
T1 - Malnutrition diagnosed by controlling nutrition status is a negative predictor of life prognosis in aortic arch aneurysm patients treated with thoracic endovascular aneurysm repair
AU - Inoue, Kentaro
AU - Matsumoto, Takuya
AU - Yamashita, Sho
AU - Yoshiga, Ryosuke
AU - Yoshiya, Keiji
AU - Matsubara, Yutaka
AU - Matsuda, Daisuke
AU - Morisaki, Koichi
AU - Furuyama, Tadashi
AU - Mori, Masaki
N1 - Publisher Copyright:
© The Author(s) 2019.
PY - 2020/2/1
Y1 - 2020/2/1
N2 - Objectives: Controlling Nutritional Status (CONUT) is a useful screening tool for malnutrition in patients with various diseases; however, how CONUT-diagnosed malnutrition affects patients with aortic arch aneurysm is unknown. This study aimed to reveal the utility of CONUT for detecting the patients with high-risk aortic arch aneurysm with malnutrition. Methods: Sixty patients treated for aortic arch aneurysms with elective thoracic endovascular aneurysm repair from 2009 to 2015 were retrospectively analyzed at a single institution. Preoperative nutrition status was evaluated by CONUT, and a CONUT score ≥ 3 was defined as malnutrition. The influence of malnutrition on the patients’ overall survival, aneurysm-related death-free rates, and prevalence of re-interventions were also analyzed. Results: Twenty-three patients were diagnosed with malnutrition. Overall survival was significantly lower in the malnutrition group (P = 0.0036). The multivariate Cox proportional hazard analysis revealed that age (P < 0.0001) and malnutrition (P = 0.0457) were negative predictors of overall survival. Conversely, the two groups did not differ significantly in aneurysm-related death-free rates (P = 0.7879) and the prevalence of re-interventions (P = 0.7879). Conclusions: Malnutrition diagnosed by CONUT as well as age is a negative predictor of survival prognosis in patients with aortic arch aneurysm.
AB - Objectives: Controlling Nutritional Status (CONUT) is a useful screening tool for malnutrition in patients with various diseases; however, how CONUT-diagnosed malnutrition affects patients with aortic arch aneurysm is unknown. This study aimed to reveal the utility of CONUT for detecting the patients with high-risk aortic arch aneurysm with malnutrition. Methods: Sixty patients treated for aortic arch aneurysms with elective thoracic endovascular aneurysm repair from 2009 to 2015 were retrospectively analyzed at a single institution. Preoperative nutrition status was evaluated by CONUT, and a CONUT score ≥ 3 was defined as malnutrition. The influence of malnutrition on the patients’ overall survival, aneurysm-related death-free rates, and prevalence of re-interventions were also analyzed. Results: Twenty-three patients were diagnosed with malnutrition. Overall survival was significantly lower in the malnutrition group (P = 0.0036). The multivariate Cox proportional hazard analysis revealed that age (P < 0.0001) and malnutrition (P = 0.0457) were negative predictors of overall survival. Conversely, the two groups did not differ significantly in aneurysm-related death-free rates (P = 0.7879) and the prevalence of re-interventions (P = 0.7879). Conclusions: Malnutrition diagnosed by CONUT as well as age is a negative predictor of survival prognosis in patients with aortic arch aneurysm.
UR - http://www.scopus.com/inward/record.url?scp=85071528957&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071528957&partnerID=8YFLogxK
U2 - 10.1177/1708538119869458
DO - 10.1177/1708538119869458
M3 - Article
C2 - 31446849
AN - SCOPUS:85071528957
SN - 1708-5381
VL - 28
SP - 31
EP - 41
JO - Vascular
JF - Vascular
IS - 1
ER -
