TY - JOUR
T1 - Malignant ovarian tumor composed of endometrioid adenocarcinoma, clear cell adenocarcinoma, squamous cell carcinoma, yolk sac tumor and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation
T2 - A case study
AU - Ohishi, Yoshihiro
AU - Kaku, Tsunehisa
AU - Kaneki, Eisuke
AU - Wake, Norio
AU - Tsuneyoshi, Masazumi
PY - 2007/5
Y1 - 2007/5
N2 - Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.
AB - Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.
UR - http://www.scopus.com/inward/record.url?scp=34247152059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247152059&partnerID=8YFLogxK
U2 - 10.1016/j.ygyno.2007.02.003
DO - 10.1016/j.ygyno.2007.02.003
M3 - Article
C2 - 17341430
AN - SCOPUS:34247152059
SN - 0090-8258
VL - 105
SP - 548
EP - 552
JO - Gynecologic Oncology
JF - Gynecologic Oncology
IS - 2
ER -