M13 Bacteriophage and Adeno-Associated Virus Hybrid for Novel Tissue Engineering Material with Gene Delivery Functions

So Young Yoo, Hyo Eon Jin, Dong Shin Choi, Masae Kobayashi, Yohan Farouz, Sky Wang, Seung Wuk Lee

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A novel hybrid phage carrying genes from prokaryotic M13 phage and eukaryotic adeno-associated viruses can be used as a tissue engineering material with gene delivery functions. The filamentous shape of the resulting hybrid phage easily forms nanofibrous matrices, which can support cellular growth in tissue culture conditions and deliver the target programmed gene information into the target cells.

Original languageEnglish
Pages (from-to)88-93
Number of pages6
JournalAdvanced Healthcare Materials
Volume5
Issue number1
DOIs
Publication statusPublished - Jan 1 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

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