Low-frequency of bacteremia after endoscopic submucosal dissection of the stomach.

Soichi Itaba, Yoichiro Iboshi, Kazuhiko Nakamura, Haruei Ogino, Yorinobu Sumida, Akira Aso, Shigetaka Yoshinaga, Hirotada Akiho, Hisato Igarashi, Masaki Kato, Kazuhiro Kotoh, Tetsuhide Ito, Ryoichi Takayanagi

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34 Citations (Scopus)


Mainstream therapy for early gastric cancer in Japan has now shifted from endoscopic mucosal resection (EMR) to endoscopic submucosal dissection (ESD). Although bacteremia is reported as being infrequent and transient in gastric EMR, there are no reports of it being investigated in gastric ESD. This study aimed to determine the frequency of bacteremia in gastric ESD. A prospective study, in 46 consecutive patients who underwent gastric ESD, investigated the frequency of bacteremia before and after the procedure. Results: The median time for the total ESD procedure was 105min (range 30-400). The median volume of the submucosal injection was 80ml (range 20-260). The mean size of the resected specimen was 40±9.7mm. Blood cultures obtained before ESD were positive in 4.4% (2/45) of cases. Bacillus subtilis and Bacillus spp. were the isolated microorganisms. Blood cultures obtained 10min after ESD were positive in 4.3% (2/46) of cases; with the same microorganisms being isolated. Blood cultures obtained 3h after ESD were all negative. No signs of sepsis were seen in the two patients with a positive blood culture 10min after ESD. The frequency of bacteremia after gastric ESD was low and transient. ESD for gastric lesions is thought to have a low risk of infectious complications; therefore, prophylactic administration of antibiotics may not be warranted.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
Issue number1
Publication statusPublished - Jan 2011

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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