[Locomotive syndrome and metabolic syndrome]

Jun-Ichi Fukushi, Yukihide Iwamoto

Research output: Contribution to journalArticlepeer-review


The Japanese Orthopedic Association coined the term locomotive syndrome (LS) to designate a condition of elderly people in high risk groups of requiring nursing care because of problems with their musculoskeletal diseases. LS is a socioeconomic concept, and closely associated with osteoporosis, osteoarthritis, and sarcopenia. Recent studies have revealed that metabolic syndrome (MS), a clustering of cardiovascular risk factors, has been related with LS. For example, individuals with MS have a greater risk of osteoarthritis and sarcopenia. Secreted factors from adipose tissue and skeletal muscles, namely, adipokines and myokines, are involved in the association of LS and MS.

Original languageEnglish
Pages (from-to)1834-1838
Number of pages5
JournalNihon rinsho. Japanese journal of clinical medicine
Issue number10
Publication statusPublished - Oct 1 2014

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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