TY - JOUR
T1 - Lipid based biocompatible ionic liquids
T2 - Synthesis, characterization and biocompatibility evaluation
AU - Uddin, Shihab
AU - Chowdhury, Md Raihan
AU - Wakabayashi, Rie
AU - Kamiya, Noriho
AU - Moniruzzaman, Muhammad
AU - Goto, Masahiro
N1 - Funding Information:
This research was supported by a Grant-in-Aid for Scientific Research (no. JP20K20440) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. S. Uddin thanks the Government of Japan for providing a MEXT scholarship and we thank Dr M. Watanabe, Prof. N. Kimizuka and Dr M. Morikawa for providing the facilities to conduct NMR, MS, DSC and optical polarized microscopic analyses.
Publisher Copyright:
© 2020 The Royal Society of Chemistry.
PY - 2020/11/18
Y1 - 2020/11/18
N2 - We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1,2-dimyristoyl-sn-glycero-3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. These materials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.
AB - We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1,2-dimyristoyl-sn-glycero-3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. These materials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.
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U2 - 10.1039/d0cc04491a
DO - 10.1039/d0cc04491a
M3 - Article
C2 - 33073787
AN - SCOPUS:85096059741
SN - 1359-7345
VL - 56
SP - 13756
EP - 13759
JO - Chemical Communications
JF - Chemical Communications
IS - 89
ER -